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CD8 alpha 抗体 (AA 28-196)

Name: CD8 alpha 抗体 (AA 28-196)
SKU: ABIN5693154
Availability: OutOfStock

CD8A 适用: 小鼠, 大鼠 FACS, IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated

Flow Cytometry analysis of EL-4 cells using anti-CD8 alpha antibody . (CD8 alpha 抗体 (AA 28-196))

FACS

Western blot analysis of CD8 alpha using anti-CD8 alpha antibody . (CD8 alpha 抗体 (AA 28-196))

IHC analysis of CD8 alpha using anti-CD8 alpha antibody . (CD8 alpha 抗体 (AA 28-196))

IHC

4 images

(2 references)

产品编号 ABIN5693154

发货至: 中国

Datasheet as PDF

抗原 See all CD8 alpha (CD8A) 抗体

CD8 alpha (CD8A) (CD8a Molecule (CD8A))
抗原表位
15

11

9

9

9

8

7

5

4

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 28-196
适用
174

100

44

36

13

6

4

3

3

3

2

2

2

1

1

1

1

1
小鼠, 大鼠
宿主
140

117

90
兔
Compatible Secondaries
克隆类型
258

83

3
多克隆
标记
127

40

27

23

20

8

8

8

6

5

5

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD8 alpha antibody is un-conjugated
应用范围
275

113

78

62

61

50

31

18

14

13

12

11

7

6

6

5

5

4

3

2

2

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA

原理

Anti-CD8 alpha/Cd8a Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-CD8 alpha/Cd8a Antibody Picoband® (ABIN5693154). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived mouse CD8 alpha recombinant protein (Position: K28-Y196).

亚型

IgG

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CD8A 适用: 小鼠 FACS, IP, IHC (fro), IHC (p), ICC, Func 宿主: 大鼠 Monoclonal 53-6-7 unconjugated

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CD8A 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 53-6-7 PE

anti-CD8a Molecule (CD8A) antibody
CD8A 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal C8-468 unconjugated

anti-CD8a Molecule (CD8A) (AA 22-182) antibody
CD8A 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 6A9A5 unconjugated

anti-CD8a Molecule (CD8A) (AA 59-88) antibody
CD8A 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. Bowcock, A. M., Kavathas, P., Margolskee, R. F., Herzenberg, L., Cavalli-Sforza, L. L. An RFLP associated with pcDLeu2-14, a human T-cell differentiation antigen CD8 (Leu2) cDNA mapped to 2p12. Nucleic Acids Res. 14: 7817 only, 1986. 2. "Entrez Gene: CD8A CD8a molecule".

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Xu, Tan, Wang, Wang, Li, Wu, Chen, Wu, Tan: "Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1501-10, (2015) (PubMed).

Zhang, Chen, Lao, Huang: "Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients." in: World journal of gastroenterology, Vol. 10, Issue 10, pp. 1436-9, (2005) (PubMed).
抗原

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

别名

Cd8a (CD8A 产品)

背景

Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.

分子量

36 kDa

基因ID

12525

UniProt

P01731

途径

TCR Signaling