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TPMT 抗体 (AA 1-245)

TPMT 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693135
发货至: 中国
  • 抗原 See all TPMT 抗体
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    抗原表位
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-245
    适用
    • 43
    • 12
    • 11
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 34
    • 9
    克隆类型
    • 31
    • 12
    多克隆
    标记
    • 26
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPMT antibody is un-conjugated
    应用范围
    • 31
    • 19
    • 17
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for TPMT detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
    免疫原
    E. coli-derived human TPMT recombinant protein (Position: M1-K245).
    Top Product
    Discover our top product TPMT Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    别名
    TPMT (TPMT 产品)
    背景

    Synonyms: Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT

    Background: Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

    UniProt
    P51580
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