HGD 抗体 (AA 374-445)
Quick Overview for HGD 抗体 (AA 374-445) (ABIN5693116)
抗原
See all HGD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 374-445
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原理
- Anti-HGD Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HGD Antibody Picoband® (ABIN5693116). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human HGD recombinant protein (Position: D374-N445).
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亚型
- IgG
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anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 1-329) antibody
HGD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 190-429) antibodyHGD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 226-445) antibodyHGD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 226-445) antibodyHGD 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 377-445) antibodyHGD 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 1-445) antibodyHGD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 1-445) antibodyHGD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 8-205) antibodyHGD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 377-445) antibodyHGD 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Homogentisate 1,2-Dioxygenase (HGD) (AA 252-301) antibodyHGD 适用: 人, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot,0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section),0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA,0.1-0.5 μg/mL
1. Fernandez-Canon, J. M., Granadino, B., Beltran-Valero de Bernabe, D., Renedo, M., Fernandez-Ruiz, E., Penalva, M. A., Rodriguez de Cordoba, S. The molecular basis of alkaptonuria. Nature Genet. 14: 19-24, 1996. 2. Vilboux, T., Kayser, M., Introne, W., Suwannarat, P., Bernardini, I., Fischer, R., O'Brien, K., Kleta, R., Huizing, M., Gahl, W. A. Mutation spectrum of homogentisic acid oxidase (HGD) in alkaptonuria. Hum. Mutat. 30: 1611-1619, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HGD (Homogentisate 1,2-Dioxygenase (HGD))
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别名
- HGD
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背景
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Synonyms: Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase, HGD, HGO
Tissue Specificity: Highest expression in the prostate, small intestine, colon, kidney and liver.
Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.
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分子量
- 50 kDa
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基因ID
- 3081
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UniProt
- Q93099
抗原
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