CRLF2 抗体 (AA 26-231)
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- 抗原 See all CRLF2 抗体
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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抗原表位
- AA 26-231
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRLF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 品牌
- Picoband™
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for CRLF2 detection. Tested with WB, ELISA(Cap) in Human.
- 免疫原
- E. coli-derived human CRLF2 recombinant protein (Position: A26-K231).
- Top Product
- Discover our top product CRLF2 Primary Antibody
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
ELISA(Cap), 1-5 μg/mL - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 别名
- CRLF2 (CRLF2 产品)
- 背景
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Synonyms: Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor, CRLF2, CRL2, ILXR, TSLPR
Tissue Specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
Background: Cytokine receptor-like factor 2 is a protein that in humans is encoded by the CRLF2 gene. This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
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