电话:: +86 (0512) 65829739
传真:: +86 (010) 6788 5057
电子邮件:: orders@antibodies-online.cn

我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

POR 抗体 (C-Term) (DyLight 488)

This anti-POR antibody is a 兔多克隆 antibody detecting POR in FACS. Suitable for 人.

产品编号 ABIN7354705

发货至: 中国

Quick Overview for POR 抗体 (C-Term) (DyLight 488) (ABIN7354705)

抗原

See all POR 抗体

POR (P450 (Cytochrome) Oxidoreductase (POR))

适用

52
28
23
4
4
4
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

42
2
2
2
2
2
2
2
2
1
1

This POR antibody is conjugated to DyLight 488

应用范围

43
28
14
10
9
9
9
8
2
2
1
1

Flow Cytometry (FACS)

Discover our top product POR Primary Antibody

抗原表位
7

6

4

3

2

2

2

2

2

1

1

1

1

1

1

1
AA 633-668, C-Term

原理

Anti-Human POR DyLight® 488 conjugated Antibody

序列

RNMARDVQNT FYDIVAELGA MEHAQAVDYI KKLMTK

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Human POR DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human POR , different from the related mouse and rat sequences by five amino acids.

亚型

IgG
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 77-518) antibody
POR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibody
POR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-250) antibody
POR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (N-Term) antibody
KO Validated POR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) antibody
POR 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibody
POR 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 2-671) antibody
POR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibody
POR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibody
KO Validated POR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 633-668), (C-Term) antibody
POR 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Adachi, M., Asakura, Y., Matsuo, M., Yamamoto, T., Hanaki, K., Arlt, W. POR R457H is a global founder mutation causing Antley-Bixler syndrome with autosomal recessive trait. (Letter) Am. J. Med. Genet. 140A: 633-635, 2006. 2. Miller, W. L. Congenital adrenal hyperplasia. (Letter) New Eng. J. Med. 314: 1321-1322, 1986. 3. Shephard, E. A., Phillips, I. R., Santisteban, I., West, L. F., Palmer, C. N., Ashworth, A., Povey, S. Isolation of a human cytochrome P-450 reductase cDNA clone and localization of the corresponding gene to chromosome 7q11.2. Ann. Hum. Genet. 53: 291-301, 1989.

限制

仅限研究用
状态

Liquid

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

Lot specific

缓冲液

Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
抗原

POR (P450 (Cytochrome) Oxidoreductase (POR))

别名

POR

背景

Synonyms: NADPH--cytochrome P450 reductase
Tissue Specificity: Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
Background: POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons ly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

分子量

39 kDa

基因ID

5447

UniProt

P16435

途径

Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome

You are here: