EPOR 抗体 (AA 32-225)
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北京 101111
Quick Overview for EPOR 抗体 (AA 32-225) (ABIN5693050)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-225
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原理
- Anti-EPO Receptor/Epor Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-EPO Receptor/Epor Antibody (ABIN5693050). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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免疫原
- E. coli-derived mouse EPO Receptor recombinant protein (Position: D32-E225).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- EPOR (Erythropoietin Receptor (EPOR))
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别名
- Epor
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背景
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Synonyms: Erythropoietin receptor, EPO-R, Epor
Tissue Specificity: Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells.
Background: The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
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分子量
- 55 kDa
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基因ID
- 13857
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UniProt
- P14753
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途径
- JAK/STAT Signaling
抗原
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