MPZ 抗体 (AA 30-153)
Quick Overview for MPZ 抗体 (AA 30-153) (ABIN5693047)
抗原
See all MPZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-153
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原理
- Anti-Myelin Protein Zero/MPZ Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Myelin Protein Zero/MPZ Antibody Picoband® (ABIN5693047). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Myelin Protein Zero recombinant protein (Position: I30-R153).
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亚型
- IgG
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anti-Myelin Protein Zero (MPZ) (AA 175-248) antibody
MPZ 适用: 大鼠, 小鼠, 犬 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (C-Term) antibodyMPZ 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 193-223), (C-Term) antibodyMPZ 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 1-258) antibodyMPZ 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 186-215), (C-Term) antibodyMPZ 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21459 unconjugated
anti-Myelin Protein Zero (MPZ) antibodyMPZ 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 30-248) antibodyMPZ 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 30-156) antibodyMPZ 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) antibodyMPZ 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (Internal Region) antibodyVerified MPZ 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Lemke G, Axel R (March 1985). "Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin". Cell. 40 (3): 501-8. 2. Sakamoto Y, Kitamura K, Yoshimura K, Nishijima T, Uyemura K (March 1987). "Complete amino acid sequence of P0 protein in bovine peripheral nerve myelin". J. Biol. Chem. 262 (9): 4208-14. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MPZ (Myelin Protein Zero (MPZ))
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别名
- MPZ
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背景
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Synonyms: Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ
Tissue Specificity: Found only in peripheral nervous system Schwann cells.
Background: Myelin protein zero (P0, MPZ) is a glycoprotein which in humans is encoded by the MPZ gene. This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism.
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分子量
- 28 kDa
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基因ID
- 4359
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UniProt
- P25189
抗原
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