MYBPC3 抗体 (AA 1070-1123)
(1 reference)Quick Overview for MYBPC3 抗体 (AA 1070-1123) (ABIN5693035)
抗原
See all MYBPC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1070-1123
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原理
- Anti-MYBPC3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MYBPC3 Antibody Picoband® (ABIN5693035). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human MYBPC3 recombinant protein (Position: Q1070-H1123).
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亚型
- IgG
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anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 200-400) antibody
MYBPC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) antibodyMYBPC3 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 189-218), (N-Term) antibodyMYBPC3 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31023 unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 1-328) antibodyMYBPC3 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (C-Term) antibodyMYBPC3 适用: 人 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 188-218), (N-Term) antibodyMYBPC3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Calore, C., De Bortoli, M., Romualdi, C., Lorenzon, A., Angelini, A., Basso, C., Thiene, G., Iliceto, S., Rampazzo, A., Melacini, P. A founder MYBPC3 mutation results in HCM with a high risk of sudden death after the fourth decade of life. J. Med. Genet. 52: 338-347, 2015. 2. Ehlermann, P., Weichenhan, D., Zehelein, J., Steen, H., Pribe, R., Zeller, R., Lehrke, S., Zugck, C., Ivandic, B. T., Katus, H. A. Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene. BMC Med. Genet. 9: 95, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imaging." in: BMC cardiovascular disorders, Vol. 15, pp. 59, (2015) (PubMed).
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: "Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imaging." in: BMC cardiovascular disorders, Vol. 15, pp. 59, (2015) (PubMed).
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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别名
- MYBPC3
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背景
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Synonyms: Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC3
Tissue Specificity: Red blood cells.
Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
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分子量
- 160 kDa
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基因ID
- 4607
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UniProt
- Q14896
抗原
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