CBX3 抗体 (AA 2-183)
Quick Overview for CBX3 抗体 (AA 2-183) (ABIN5693033)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-183
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原理
- Anti-HP1 gamma/CBX3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HP1 gamma/CBX3 Antibody Picoband® (ABIN5693033). Tested in ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human HP1 gamma recombinant protein (Position: A2-Q183).
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亚型
- IgG
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anti-Chromobox Homolog 3 (CBX3) (Internal Region) antibody
Verified CBX3 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6D1C4 unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12-1D9 unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) antibodyCBX3 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) antibodyCBX3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (Internal Region) antibodyCBX3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (Middle Region) antibodyCBX3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)". 2. Koike, N, Maita H, Taira T, Ariga H, Iguchi-Ariga S M (February 2000). "Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)". FEBS Lett. NETHERLANDS. 467 (1): 17-21. 3. Ye, Q, Worman H J (June 1996). "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1". J. Biol. Chem. UNITED STATES. 271(25): 14653-6. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- CBX3
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背景
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Synonyms: Chromobox protein homolog 3, HECH, Heterochromatin protein 1 homolog gamma, HP1 gamma, Modifier 2 protein, CBX3
Tissue Specificity: Widely expressed. Expressed at the highest levels in pancreas, heart, brain, skeletal muscle and placenta. Expressed at lower levels in lung, liver and kidney.
Background: Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
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分子量
- 21 kDa
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基因ID
- 11335
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UniProt
- Q13185
抗原
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