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NCR1 抗体 (AA 22-258)

NCR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693031
发货至: 中国
  • 抗原 See all NCR1 抗体
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    抗原表位
    • 15
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-258
    适用
    • 71
    • 55
    • 18
    • 9
    • 5
    • 3
    • 3
    人, 小鼠, 大鼠
    宿主
    • 60
    • 25
    • 9
    • 2
    克隆类型
    • 60
    • 32
    • 3
    多克隆
    标记
    • 40
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCR1 antibody is un-conjugated
    应用范围
    • 44
    • 34
    • 20
    • 13
    • 13
    • 11
    • 11
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    Anti-NCR1 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-NCR1 Antibody Picoband® (ABIN5693031). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    免疫原
    E. coli-derived human NCR1 recombinant protein (Position: Q22-R258).
    亚型
    IgG
    Top Product
    Discover our top product NCR1 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., Hanna, J., Qimron, U., Landau, G., Greenbaum, E., Zakay-Rones, Z., Porgador, A., Mandelboim, O. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature Immun. 7: 517-523, 2006. 2. Vankayalapati, R., Wizel, B., Weis, S. E., Safi, H., Lakey, D. L., Mandelboim, O., Samten, B., Porgador, A., Barnes, P. F. The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium. J. Immun. 168: 3451-3457, 2002.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    别名
    NCR1 (NCR1 产品)
    背景

    Synonyms: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94

    Tissue Specificity: Selectively expressed by both resting and activated NK cells.

    Background: Natural cytotoxicity triggering receptor 1, also known as NKp46, is a protein that in humans is encoded by the NCR1 gene. This gene is mapped to chromosome 19, where genes encoding other NK inhibitory and activator structures are also located. NKP46 participates in NK-cell-mediated lysis of cells infected with an intracellular bacterium and that reduced functional capacity of NK cells is associated with severe manifestations of infectious disease.

    分子量
    36 kDa
    基因ID
    9437
    UniProt
    O76036
    途径
    Regulation of Leukocyte Mediated Immunity
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