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NCR1 抗体 (AA 22-258)

This anti-NCR1 antibody is a 兔 多克隆 antibody detecting NCR1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5693031
发货至: 中国

Quick Overview for NCR1 抗体 (AA 22-258) (ABIN5693031)

抗原

See all NCR1 抗体
NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

适用

  • 74
  • 57
  • 19
  • 9
  • 5
  • 3
  • 3
人, 小鼠, 大鼠

宿主

  • 64
  • 25
  • 9
  • 2

克隆类型

  • 64
  • 32
  • 3
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NCR1 antibody is un-conjugated

应用范围

  • 48
  • 34
  • 21
  • 13
  • 13
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  • 11
  • 7
  • 7
  • 6
  • 4
  • 3
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-258

    原理

    Anti-NCR1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-NCR1 Antibody Picoband® (ABIN5693031). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human NCR1 recombinant protein (Position: Q22-R258).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., Hanna, J., Qimron, U., Landau, G., Greenbaum, E., Zakay-Rones, Z., Porgador, A., Mandelboim, O. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature Immun. 7: 517-523, 2006. 2. Vankayalapati, R., Wizel, B., Weis, S. E., Safi, H., Lakey, D. L., Mandelboim, O., Samten, B., Porgador, A., Barnes, P. F. The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium. J. Immun. 168: 3451-3457, 2002.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

    别名

    NCR1

    背景

    Synonyms: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94

    Tissue Specificity: Selectively expressed by both resting and activated NK cells.

    Background: Natural cytotoxicity triggering receptor 1, also known as NKp46, is a protein that in humans is encoded by the NCR1 gene. This gene is mapped to chromosome 19, where genes encoding other NK inhibitory and activator structures are also located. NKP46 participates in NK-cell-mediated lysis of cells infected with an intracellular bacterium and that reduced functional capacity of NK cells is associated with severe manifestations of infectious disease.

    分子量

    36 kDa

    基因ID

    9437

    UniProt

    O76036

    途径

    Regulation of Leukocyte Mediated Immunity
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