Neurexin 1 抗体 (AA 141-294)
Quick Overview for Neurexin 1 抗体 (AA 141-294) (ABIN5693015)
抗原
See all Neurexin 1 (NRXN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 141-294
-
原理
- Anti-Neurexin 1/NRXN1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Neurexin 1/NRXN1 Antibody Picoband® (ABIN5693015). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
免疫原
- E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).
-
亚型
- IgG
-
-
anti-Neurexin 1 (NRXN1) (AA 184-363) antibody
NRXN1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (C-Term) antibodyVerified NRXN1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (N-Term) antibodyNRXN1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-130) antibodyNRXN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-130) antibodyNRXN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-310) antibodyNRXN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-310) antibodyNRXN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 77-110), (N-Term) antibodyNRXN1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB52794 unconjugated
anti-Neurexin 1 (NRXN1) (AA 1328-1421) antibodyNRXN1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 546-560), (Extracellular) antibodyNRXN1 适用: 大鼠 WB, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Comoletti, Davide, Flynn Robyn, Jennings Lori L, Chubykin Alexander, Matsumura Takehito, Hasegawa Hana, Südhof Thomas C, Taylor Palmer (Dec 2003). "Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta". J. Biol. Chem. United States. 278 (50): 50497-50505. 2. Nguyen T, Südhof TC (1997). "Binding properties of neuroligin 1 and neurexin 1beta reveal function as heterophilic cell adhesion molecules". J. Biol. Chem. 272 (41): 26032-26039. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Neurexin 1 (NRXN1)
-
别名
- NRXN1
-
背景
-
Synonyms: Neurexin-1-beta, Neurexin I-beta, NRXN1
Tissue Specificity: Predominantly expressed in the liver (PubMed:11099417, PubMed:11452359). Low expression levels in the small intestine and colon (PubMed:11099417). Very low levels in other tissues, including brain, heart and spleen (PubMed:11452359).
Background: Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
-
分子量
- 160-170 kDa
-
基因ID
- 9378
-
UniProt
- P58400
-
途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
-
