CES1 抗体 (AA 99-206)
Quick Overview for CES1 抗体 (AA 99-206) (ABIN5693010)
抗原
See all CES1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 99-206
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原理
- Anti-Liver Carboxylesterase 1/CES1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Liver Carboxylesterase 1/CES1 Antibody Picoband® (ABIN5693010). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human CES1 recombinant protein (Position: E99-A206).
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亚型
- IgG
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anti-Carboxylesterase 1 (CES1) (AA 19-300) antibody
CES1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (AA 18-299) antibodyCES1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (AA 291-566) antibodyCES1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (AA 287-566) antibodyCES1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) antibodyCES1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Carboxylesterase 1 (CES1) (AA 31-286) antibodyCES1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (Internal Region) antibodyVerified CES1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (AA 1-566) antibodyCES1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (AA 1-566) antibodyCES1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Carboxylesterase 1 (CES1) (C-Term) antibodyCES1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: CES1 carboxylesterase 1 (monocyte/macrophage serine esterase 1)". 2. Markey GM (Feb 2011). "Carboxylesterase 1 (Ces1): from monocyte marker to major player". J Clin Pathol. 64 (2): 107-9. 3. Zhu HJ, Appel DI, Johnson JA, Chavin KD, Markowitz JS (Jan 2009). "Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril". Biochem Pharmacol. 77 (7): 1266-72. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CES1 (Carboxylesterase 1 (CES1))
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别名
- CES1
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背景
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Synonyms: Liver carboxylesterase 1, Acyl-coenzyme A:cholesterol acyltransferase, ACAT, Brain carboxylesterase hBr1, Carboxylesterase 1, CE-1, hCE-1
Tissue Specificity: Expressed predominantly in liver with lower levels in heart and lung.
Background: Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene. This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
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分子量
- 62 kDa
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基因ID
- 1066
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UniProt
- P23141
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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