HTRA1 抗体
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北京 101111
Quick Overview for HTRA1 抗体 (ABIN5692999)
抗原
See all HTRA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-HTRA1 Antibody
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序列
- QLRAASRRSE RLHRPPVIVL QRGACGQGQE DPNSLRHKYN FIAD
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HTRA1 Antibody (ABIN5692999). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HTRA1, which shares 93.2% amino acid (aa) sequence identity with both mouse and rat HTRA1.
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亚型
- IgG
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anti-HtrA Serine Peptidase 1 (HTRA1) (AA 116-147), (N-Term) antibody
HTRA1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02326 unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 23-248) antibodyHTRA1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) antibodyHTRA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 204-364) antibodyHTRA1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 304-442) antibodyHTRA1 适用: E. coli WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 381-412), (C-Term) antibodyHTRA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02327 unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 122-171) antibodyHTRA1 适用: 人, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (N-Term) antibodyHTRA1 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 389-419), (C-Term) antibodyHTRA1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
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别名
- HTRA1
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背景
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Synonyms: Serine protease HTRA1, High-temperature requirement A serine peptidase 1, L56, Serine protease 11, HTRA1, HTRA, PRSS11
Tissue Specificity: Widely expressed, with strongest expression in placenta (at protein level). Secreted by synovial fibroblasts. Up- regulated in osteoarthritis and rheumatoid arthritis synovial fluids and cartilage as compared with non-arthritic (at protein level).
Background: Serine protease HTRA1 is an enzyme that in humans is encoded by the HTRA1 gene. This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
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分子量
- 51 kDa
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基因ID
- 5654
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UniProt
- Q92743
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途径
- Growth Factor Binding
抗原
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