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alpha Fetoprotein 抗体 (AA 19-254)

This anti-alpha Fetoprotein antibody is a 兔 多克隆 antibody detecting alpha Fetoprotein in WB 和 ELISA. Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN5692976
发货至: 中国

Quick Overview for alpha Fetoprotein 抗体 (AA 19-254) (ABIN5692976)

抗原

See all alpha Fetoprotein (AFP) 抗体
alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This alpha Fetoprotein antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 19-254

    原理

    Anti-Alpha 1 Fetoprotein/Afp Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Alpha 1 Fetoprotein/Afp Antibody Picoband® (ABIN5692976). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived mouse Alpha 1 Fetoprotein recombinant protein (Position: K19-L254).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Bader D, Riskin A, Vafsi O, Tamir A, Peskin B, Israel N, Merksamer R, Dar H, David M (November 2004). "Alpha-fetoprotein in the early neonatal period--a large study and review of the literature". Clin. Chim. Acta 349 (1-2): 15-23. 2. Blair JI, Carachi R, Gupta R, Sim FG, McAllister EJ, Weston R (April 1987). "Plasma alpha fetoprotein reference ranges in infancy: effect of prematurity". Arch. Dis. Child. 62 (4): 362-9. 3. Carter CS (2002). "Neuroendocrinology of sexual behavior in the female". In Becker JB. Behavioral Endocrinology. Cambridge, Mass: MIT Press. pp.88-89. ISBN 0-262-52321-3

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Jeng, Jeng, Jeng, Sheen, Li, Lu, Chang: "Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells." in: American journal of surgery, Vol. 215, Issue 4, pp. 735-743, (2017) (PubMed).

    Winkler, Hempel, Brückner, Mallek, Weise, Liehr, Tautenhahn, Bartels, Christ: "Mouse white adipose tissue-derived mesenchymal stem cells gain pericentral and periportal hepatocyte features after differentiation in vitro, which are preserved in vivo after hepatic transplantation." in: Acta physiologica (Oxford, England), Vol. 215, Issue 2, pp. 89-104, (2016) (PubMed).

    Yan, Zhu, Sun, Zhang, Li, Sun, Li, Qian, Zhu, Xu: "Extracellular regulated protein kinases 1/2 phosphorylation is required for hepatic differentiation of human umbilical cord-derived mesenchymal stem cells." in: Experimental biology and medicine (Maywood, N.J.), Vol. 240, Issue 4, pp. 534-45, (2015) (PubMed).

    Shan, Wu, Li, Shen, Wang, Liu, Shen, Lei: "Continuous passages accelerate the reprogramming of mouse induced pluripotent stem cells." in: Cellular reprogramming, Vol. 16, Issue 1, pp. 77-83, (2014) (PubMed).

    Wang, Xu, Zhou, Zhong, Wen, Yu, Chen, Shen, Chen, She, Jiang, Miao, Wei: "The viral oncoprotein HBx of Hepatitis B virus promotes the growth of hepatocellular carcinoma through cooperating with the cellular oncoprotein RMP." in: International journal of biological sciences, Vol. 10, Issue 10, pp. 1181-92, (2014) (PubMed).

    Yang, Gu, Zheng, Li, Lian, Miao, Jiang, Wei: "RPB5-mediating protein is required for the proliferation of hepatocellular carcinoma cells." in: The Journal of biological chemistry, Vol. 286, Issue 13, pp. 11865-74, (2011) (PubMed).

  • 抗原

    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

    别名

    Afp

    背景

    Synonyms: Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, Afp

    Tissue Specificity: Plasma.

    Background: RAC-gamma serine/threonine-protein kinase, also known as protein kinase Akt-3, is an enzyme that in humans is encoded by the AKT3 gene. This gene is mapped to 1q43-q44. The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor(PDGF), insulin, and insulin-like growth factor 1(IGF1). AKT3 plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. This gene is required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands.

    分子量

    69 kDa

    基因ID

    11576

    UniProt

    P02772

    途径

    C21-Steroid Hormone Metabolic Process
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