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SPR 抗体 (AA 36-261)

This anti-SPR antibody is a 兔 多克隆 antibody detecting SPR in WB 和 ELISA. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN5692972
发货至: 中国

Quick Overview for SPR 抗体 (AA 36-261) (ABIN5692972)

抗原

See all SPR 抗体
SPR (Sepiapterin Reductase (SPR))

适用

  • 57
  • 29
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  • 1
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  • 1
人, 小鼠

宿主

  • 47
  • 13

克隆类型

  • 50
  • 10
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SPR antibody is un-conjugated

应用范围

  • 53
  • 17
  • 13
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  • 10
  • 6
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 36-261

    原理

    Anti-SPR Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SPR Antibody Picoband® (ABIN5692972). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human SPR recombinant protein (Position: V36-K261).

    亚型

    IgG
  • 应用备注

    Western blot,0.1-0.5 μg/mL
    ELISA,0.1-0.5 μg/mL
    1. "Entrez Gene: SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)". 2. Ichinose H, Katoh S, Sueoka T, Titani K, Fujita K, Nagatsu T (Oct 1991). "Cloning and sequencing of cDNA encoding human sepiapterin reductase--an enzyme involved in tetrahydrobiopterin biosynthesis". Biochem Biophys Res Commun. 179 (1): 183-189. 3. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (1-3): 94-98.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Hu, Wang, Rao, Zhao, Yang, Hu, He, Xia, Liu, Zhen, Di, Xie, Xia, Zhu: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).

  • 抗原

    SPR (Sepiapterin Reductase (SPR))

    别名

    SPR

    背景

    Synonyms: Sepiapterin reductase, SPR, SPR

    Background: Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

    分子量

    28 kDa

    基因ID

    6697

    UniProt

    P35270

    途径

    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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