IL-27 抗体 (AA 29-234)
Quick Overview for IL-27 抗体 (AA 29-234) (ABIN5692968)
抗原
See all IL-27 (IL27) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-234
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原理
- Anti-IL27 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-IL27 Antibody Picoband® (ABIN5692968). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived mouse IL27 recombinant protein (Position: F29-S234).
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亚型
- IgG
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应用备注
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Western blot,0.1-0.5 μg/mL
ELISA,0.1-0.5 μg/mL
1. Meka, Rakeshchandra R., Venkatesha, Shivaprasad H., Dudics, Steven, Acharya, Bodhraj, Moudgil, Kamal D. "IL-27-induced modulation of autoimmunity and its therapeutic potential". Autoimmunity Reviews. 14 (12): 1131-1141. 2. Yoshimoto, Takayuki, Chiba, Yukino, Furusawa, Jun-Ichi, Xu, Mingli, Tsunoda, Ren, Higuchi, Kaname, Mizoguchi, Izuru (2015-09-01). "Potential clinical application of interleukin-27 as an antitumor agent". Cancer Science. 106 (9): 1103-1110. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL-27 (IL27) (Interleukin 27 (IL27))
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别名
- Il27
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背景
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Synonyms: Interleukin-27 subunit alpha, IL-27 subunit alpha, IL-27-A, IL27-A, p28, Il27, Il27a
Tissue Specificity: Expressed in macrophages and dendritic cells.
Background: Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
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分子量
- 29 kDa
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基因ID
- 246779
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UniProt
- Q8K3I6
抗原
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