SYT1 抗体
Quick Overview for SYT1 抗体 (ABIN5692948)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Synaptotagmin 1/SYT1 Antibody Picoband®
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序列
- RRPIAQWHTL QVEEEVDAML AVKK
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Synaptotagmin 1/SYT1 Antibody Picoband® (ABIN5692948). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Synaptotagmin 1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (pSer309) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 301-523) antibodySYT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-423) antibodySYT1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A6 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Fernandez-Chacon, R., Konigstorfer, A., Gerber, S. H., Garcia, J., Matos, M. F., Stevens, C. F., Brose, N., Rizo, J., Rosenmund, C., Sudhof, T. C. Synaptotagmin I functions as a calcium regulator of release probability. Nature 410: 41-49, 2001. 2. Poskanzer, K. E., Marek, K. W., Sweeney, S. T., Davis, G. W. Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo. Nature 426: 559-563, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SYT1 (Synaptotagmin I (SYT1))
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别名
- SYT1
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背景
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Synonyms: Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT
Tissue Specificity: Expressed in melanocytes (PubMed:23999003).
Background: Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.
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分子量
- 65 kDa
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基因ID
- 6857
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UniProt
- P21579
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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