RALBP1 抗体 (AA 239-506) (DyLight 488)
Quick Overview for RALBP1 抗体 (AA 239-506) (DyLight 488) (ABIN7354620)
抗原
See all RALBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 239-506
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原理
- Anti-Human RALBP1 DyLight® 488 conjugated Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human RALBP1 DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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免疫原
- E. coli-derived human RALBP1 recombinant protein (Position: K239-Q506).
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亚型
- IgG
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. "Entrez Gene: RALBP1 ralA binding protein 1". 2. Kashatus, D. F., Lim, K.-H., Brady, D. C., Pershing, N. L. K., Cox, A. D., Counter, C. M. RALA and RALBP1 regulate mitochondrial fission at mitosis. Nature Cell Biol. 13: 1108-1115, 2011.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- RALBP1 (RalA Binding Protein 1 (RALBP1))
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别名
- RALBP1
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背景
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Synonyms: RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76
Background: RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene. Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS, which in turn is activated by RAS. RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL. RALBP1 is also the dominant transporter of lipid peroxidation-derived glutathione conjugates and participates in several mitotic events, including inactivation of endocytosis and separation and polar movement of centrioles and appropriate distribution of mitochondria to daughter cells following mitosis.
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分子量
- 39 kDa
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基因ID
- 10928
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UniProt
- Q15311
抗原
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