PROC 抗体 (AA 200-461)
Our Local Distributor
北京 101111
Quick Overview for PROC 抗体 (AA 200-461) (ABIN5692923)
抗原
See all PROC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 200-461
-
原理
- Anti-Protein C/PROC Antibody
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Protein C/PROC Antibody (ABIN5692923). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
免疫原
- E. coli-derived human Protein C recombinant protein (Position: D200-P461).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot,0.1-0.5 μg/mL
ELISA,0.1-0.5 μg/mL
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- PROC (Vitamin K-dependent protein C (PROC))
-
别名
- PROC
-
背景
-
Synonyms: Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide, PROC
Tissue Specificity: Plasma, synthesized in the liver.
Background: Protein C (PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
-
分子量
- 52 kDa
-
基因ID
- 5624
-
UniProt
- P04070
抗原
-