PON1 抗体 (AA 30-274)
Quick Overview for PON1 抗体 (AA 30-274) (ABIN5692913)
抗原
See all PON1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 30-274
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原理
- Anti-PON1 Antibody Picoband® (monoclonal, 9D3)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PON1 Antibody Picoband® (monoclonal, 9D3) (ABIN5692913). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived mouse PON1 recombinant protein (Position: A30-D274).
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亚型
- IgG2b
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anti-Paraoxonase 1 (PON1) (AA 20-155) antibody
PON1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4G8D3 unconjugated
anti-Paraoxonase 1 (PON1) (AA 20-155) antibodyPON1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4G8A12 unconjugated
anti-Paraoxonase 1 (PON1) antibodyPON1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Paraoxonase 1 (PON1) (AA 2-186) antibodyPON1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paraoxonase 1 (PON1) antibodyPON1 适用: 人, 猴 WB, FACS 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Paraoxonase 1 (PON1) (AA 35-206) antibodyPON1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paraoxonase 1 (PON1) (AA 187-354) antibodyPON1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paraoxonase 1 (PON1) (AA 2-355) antibodyPON1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paraoxonase 1 (PON1) antibodyPON1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paraoxonase 1 (PON1) (AA 246-355) antibodyPON1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H7 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA (Cap), 1-5 μg/mL1. Costa LG, Cole TB, Vitalone A, Furlong CE (2005). "Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity". CLINICA CHEMICA ACTA 352 (1-2): 37-47. 2. Khateeb J, Gantman A, Kreitenberg AJ, Aviram M, Fuhrman B (January 2010). "Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway".Atherosclerosis 208 (1): 119-25. 3. Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN (May 1996). "The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family". Genomics 33 (3): 498-507. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PON1 (Paraoxonase 1 (PON1))
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别名
- Pon1
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背景
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Synonyms: Serum paraoxonase/arylesterase 1, PON 1
Tissue Specificity: Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.
Background: Isocitrate dehydrogenase [NADP], mitochondrialis anenzymethat in humans is encoded by theIDH2gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
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分子量
- 40 kDa
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基因ID
- 18979
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UniProt
- P52430
抗原
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