Neuromedin U 抗体
Quick Overview for Neuromedin U 抗体 (ABIN5692905)
抗原
See all Neuromedin U (NMU) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-NMU Antibody Picoband®
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序列
- FRVDEEFQSP FASQSRGYFL FRPRN
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human
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产品特性
- Anti-NMU Antibody Picoband® (ABIN5692905). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human NMU, which shares 64% and 56% amino acid (aa) sequence identity with mouse and rat NMU, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
1. Austin, C., Lo, G., Nandha, K. A., Meleagros, L., Bloom, S. R. Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract. J. Molec. Endocr. 14: 157-169, 1995. 2. Howard, A. D., Wang, R., Pong, S.-S., Mellin, T. N., Strack, A., Guan, X.-M., Zeng, Z., Williams, D. L., Jr., Feighner, S. D., Nunes, C. N., Murphy, B., Stair, J. N., and 13 others. Identification of receptors for neuromedin U and its role in feeding. Nature 406: 70-74, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Neuromedin U (NMU)
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别名
- NMU
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背景
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Synonyms: Neuromedin-U, Neuromedin-U-25, NmU-25, NMU
Tissue Specificity: Expressed throughout the enteric nervous system with highest levels being found in the jejunum.
Background: Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.
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分子量
- 26 kDa
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基因ID
- 10874
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UniProt
- P48645
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途径
- Feeding Behaviour, Photoperiodism
抗原
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