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MVP 抗体 (AA 2-259) (DyLight 488)

This anti-MVP antibody is a 兔 多克隆 antibody detecting MVP in FACS. Suitable for 人.
产品编号 ABIN7354536
发货至: 中国

Quick Overview for MVP 抗体 (AA 2-259) (DyLight 488) (ABIN7354536)

抗原

See all MVP 抗体
MVP (Major Vault Protein (MVP))

适用

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宿主

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克隆类型

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多克隆

标记

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This MVP antibody is conjugated to DyLight 488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 2-259

    原理

    Anti-Human MVP DyLight® 488 conjugated Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Human MVP DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

    免疫原

    E. coli-derived human MVP recombinant protein (Position: A2-H259).

    亚型

    IgG
  • 应用备注

    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. "Entrez Gene: MVP major vault protein". 2. Izquierdo MA, Scheffer GL, Flens MJ, Schroeijers AB, van der Valk P, Scheper RJ (Jun 1996). "Major vault protein LRP-related multidrug resistance". European Journal of Cancer. 32A (6): 979-84.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
  • 抗原

    MVP (Major Vault Protein (MVP))

    别名

    MVP

    背景

    Synonyms: Major vault protein, MVP, Lung resistance-related protein, MVP, LRP

    Tissue Specificity: Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.

    Background: Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

    分子量

    39 kDa

    基因ID

    9961

    UniProt

    Q14764
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