MYF5 抗体 (AA 25-146)
Quick Overview for MYF5 抗体 (AA 25-146) (ABIN5692895)
抗原
See all MYF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-146
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原理
- Anti-Myf5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Myf5 Antibody Picoband® (ABIN5692895). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Myf5 recombinant protein (Position: E25-Y146).
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亚型
- IgG
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anti-Myogenic Factor 5 (MYF5) (AA 7-36) antibody
MYF5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (N-Term) antibodyMYF5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (N-Term) antibodyMYF5 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 山羊, 豚鼠, 马, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (Center) antibodyMYF5 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (AA 21-70) antibodyMYF5 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (AA 1-255) antibodyMYF5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (AA 61-110) antibodyMYF5 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (Internal Region) antibodyVerified MYF5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (AA 51-100) antibodyMYF5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Factor 5 (MYF5) (AA 71-120) antibodyMYF5 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴, 山羊, 豚鼠, 马, 绵羊, 斑马鱼, 小鸡, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Gustafsson MK, Pan H, Pinney DF, Liu Y, Lewandowski A, Epstein DJ, Emerson CP (January 2002). "Myf5 is a target of long-range Shh signaling and Gli regulation for muscle specification". Genes & Development. 16 (1): 114-26. 2. Ott MO, Bober E, Lyons G, Arnold H, Buckingham M (April 1991). "Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo". Development. 111 (4): 1097-107. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MYF5 (Myogenic Factor 5 (MYF5))
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别名
- MYF5
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背景
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Synonyms: Myogenic factor 5, Myf-5, Class C basic helix-loop-helix protein 2, bHLHc2, MYF5, BHLHC2
Tissue Specificity: Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.
Background: Myogenic factor 5 is a protein that in humans is encoded by the MYF5 gene. It is a protein with a key role in regulating muscle differentiation or myogenesis, specifically the development of skeletal muscle. Myf5 belongs to a family of proteins known as myogenic regulatory factors (MRFs). This transcription factor is the earliest of all MRFs to be expressed in the embryo, where it is only markedly expressed for a few days (specifically around 8 days post-somite formation and lasting until day 14 post-somite in mice). It functions during that time to commit myogenic precursor cells to become skeletal muscle. In fact, its expression in proliferating myoblasts has led to its classification as a determination factor. Furthermore, Myf5 is a master regulator of muscle development, possessing the ability to induce a muscle phenotype upon its forced expression in fibroblastic cells.
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分子量
- 28 kDa
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基因ID
- 4617
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UniProt
- P13349
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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