MXD1 抗体 (AA 1-221)
Quick Overview for MXD1 抗体 (AA 1-221) (ABIN5692892)
抗原
See all MXD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-221
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原理
- Anti-Mad/MXD1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Mad/MXD1 Antibody Picoband® (ABIN5692892). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Mad recombinant protein (Position: M1-L221).
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亚型
- IgG
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anti-MAX Dimerization Protein 1 (MXD1) (C-Term) antibody
MXD1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 60-149) antibodyMXD1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G10 unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 60-150) antibodyMXD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2G10 unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 681-730) antibodyMXD1 适用: 小鼠, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (N-Term) antibodyMXD1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬, 马, 斑马鱼, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 1-221) antibodyMXD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Edelhoff, S., Ayer, D. E., Zervos, A. S., Steingrimsson, E., Jenkins, N. A., Copeland, N. G., Eisenman, R. N., Brent, R., Disteche, C. M. Mapping of two genes encoding members of a distinct subfamily of MAX interacting proteins: MAD to human chromosome 2 and mouse chromosome 6, and MXI1 to chromosome 10 and mouse chromosome 19. Oncogene 9: 665-668, 1994. 2. Shapiro, D. N., Valentine, V., Eagle, L., Yin, X., Morris, S. W., Prochownik, E. V. Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25. Genomics 23: 282-285, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MXD1 (MAX Dimerization Protein 1 (MXD1))
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别名
- MXD1
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背景
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Synonyms: Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD
Background: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 28 kDa
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基因ID
- 4084
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UniProt
- Q05195
抗原
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