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MXD1 抗体 (AA 1-221)

MXD1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5692892
发货至: 中国
  • 抗原 See all MXD1 抗体
    MXD1 (MAX Dimerization Protein 1 (MXD1))
    抗原表位
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-221
    适用
    • 20
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    • 3
    克隆类型
    • 19
    • 3
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    This MXD1 antibody is un-conjugated
    应用范围
    • 20
    • 12
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Anti-Mad/MXD1 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-Mad/MXD1 Antibody Picoband® (ABIN5692892). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    免疫原
    E. coli-derived human Mad recombinant protein (Position: M1-L221).
    亚型
    IgG
    Top Product
    Discover our top product MXD1 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Edelhoff, S., Ayer, D. E., Zervos, A. S., Steingrimsson, E., Jenkins, N. A., Copeland, N. G., Eisenman, R. N., Brent, R., Disteche, C. M. Mapping of two genes encoding members of a distinct subfamily of MAX interacting proteins: MAD to human chromosome 2 and mouse chromosome 6, and MXI1 to chromosome 10 and mouse chromosome 19. Oncogene 9: 665-668, 1994. 2. Shapiro, D. N., Valentine, V., Eagle, L., Yin, X., Morris, S. W., Prochownik, E. V. Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25. Genomics 23: 282-285, 1994.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    MXD1 (MAX Dimerization Protein 1 (MXD1))
    别名
    MXD1 (MXD1 产品)
    背景

    Synonyms: Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD

    Background: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    分子量
    28 kDa
    基因ID
    4084
    UniProt
    Q05195
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