MAX 抗体 (AA 30-106)
Quick Overview for MAX 抗体 (AA 30-106) (ABIN5692891)
抗原
See all MAX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-106
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原理
- Anti-MAX Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MAX Antibody Picoband® (ABIN5692891). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human MAX recombinant protein (Position: A30-R106).
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亚型
- IgG
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anti-MYC Associated Factor X (MAX) (C-Term) antibody
Verified MAX 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (AA 1-151) antibodyMAX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4E10-1A9 unconjugated
anti-MYC Associated Factor X (MAX) (AA 1-58) antibodyMAX 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (AA 1-151) antibodyMAX 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (N-Term) antibodyMAX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (AA 1-160) antibodyMAX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (pSer11) antibodyMAX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (AA 2-160) antibodyMAX 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (Middle Region) antibodyMAX 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-MYC Associated Factor X (MAX) (C-Term) antibodyMAX 适用: 人, 小鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry(Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Blackwood, E., Eisenman, R. N. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.Science 251: 1211-1217, 1991. 2. Gilladoga, A. D., Edelhoff, S., Blackwood, E. M., Eisenman, R. N., Disteche, C. M. Mapping of MAX to human chromosome 14 and mouse chromosome 12 by in situ hybridization. Oncogene 7: 1249-1251, 1992. 3. Hopewell, R., Ziff, E. B. The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max. Molec. Cell Biol. 15: 3470-3478, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAX (MYC Associated Factor X (MAX))
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别名
- MAX
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背景
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Synonyms: Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X, MAX, BHLHD4
Tissue Specificity: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Background: MAX (Max protein), also called Myc-associated factor x, is the most conserved dimerization component of the MYC-MAX-MXD1 network of basic helix-loop-helix leucine zipper (bHLHZ) transcription factors that regulate cell proliferation, differentiation, and apoptosis. The conservation of the MAX sequence is particularly high in the bHLHZ domain, which is involved in protein-protein interactions and DNA binding. The MAX gene is located on chromosome 14q23 by fluorescence in situ chromosomal hybridization. Both quasisymmetric heterodimers resemble the symmetric MAX homodimer, albeit with marked structural differences in the coiled-coil leucine zipper regions that explain preferential homo- and heteromeric dimerization of these 3 evolutionarily related DNA-binding proteins. MAX acts as a classic tumor suppressor gene. Normal lymphocytes from patients showed absence of methylation of the MAX promoter and biallelic expression of MAX, which ruled out an imprinting-mediated effect on MAX expression. The ability of these cells to divide, differentiate, and apoptose in the absence of Max demonstrated for the first time that these processes can occur via Max- and possibly Myc-independent mechanisms.
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分子量
- 19-21 kDa
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基因ID
- 4149
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UniProt
- P61244
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途径
- Mitotic G1-G1/S Phases
抗原
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