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MAX 抗体 (AA 30-106)

Name: MAX 抗体 (AA 30-106)
SKU: ABIN5692891
Availability: OutOfStock

MAX 适用: 人, 小鼠 WB, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

Western blot analysis of MAX using anti-MAX antibody . (MAX 抗体 (AA 30-106))

IHC analysis of MAX using anti-MAX antibody . (MAX 抗体 (AA 30-106))

IHC

4 images

产品编号 ABIN5692891

发货至: 中国

Datasheet as PDF

抗原 See all MAX 抗体

MAX (MYC Associated Factor X (MAX))
抗原表位
14

14

9

6

5

3

3

2

2

2

2

1

1

1
AA 30-106
适用
74

22

20

6

6

4

3

2

2

2

2

1

1

1

1
人, 小鼠
宿主
71

2

1
兔
Compatible Secondaries
克隆类型
72

2
多克隆
标记
30

5

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This MAX antibody is un-conjugated
应用范围
34

24

24

23

9

7

7

6

3

2

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

原理

Anti-MAX Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-MAX Antibody Picoband® (ABIN5692891). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human MAX recombinant protein (Position: A30-R106).

亚型

IgG

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anti-MYC Associated Factor X (MAX) (AA 1-151) antibody
MAX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4E10-1A9 unconjugated

anti-MYC Associated Factor X (MAX) (AA 1-58) antibody
MAX 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (AA 1-151) antibody
MAX 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (N-Term) antibody
MAX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (AA 2-160) antibody
MAX 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (Middle Region) antibody
MAX 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (pSer11) antibody
MAX 适用: 人 IF 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (C-Term) antibody
MAX 适用: 人, 小鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (Middle Region) antibody
MAX 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-MYC Associated Factor X (MAX) (N-Term) antibody
MAX 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. Blackwood, E., Eisenman, R. N. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.Science 251: 1211-1217, 1991. 2. Gilladoga, A. D., Edelhoff, S., Blackwood, E. M., Eisenman, R. N., Disteche, C. M. Mapping of MAX to human chromosome 14 and mouse chromosome 12 by in situ hybridization. Oncogene 7: 1249-1251, 1992. 3. Hopewell, R., Ziff, E. B. The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max. Molec. Cell Biol. 15: 3470-3478, 1995.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

MAX (MYC Associated Factor X (MAX))

别名

MAX (MAX 产品)

背景

Synonyms: Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X, MAX, BHLHD4
Tissue Specificity: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Background: MAX (Max protein), also called Myc-associated factor x, is the most conserved dimerization component of the MYC-MAX-MXD1 network of basic helix-loop-helix leucine zipper (bHLHZ) transcription factors that regulate cell proliferation, differentiation, and apoptosis. The conservation of the MAX sequence is particularly high in the bHLHZ domain, which is involved in protein-protein interactions and DNA binding. The MAX gene is located on chromosome 14q23 by fluorescence in situ chromosomal hybridization. Both quasisymmetric heterodimers resemble the symmetric MAX homodimer, albeit with marked structural differences in the coiled-coil leucine zipper regions that explain preferential homo- and heteromeric dimerization of these 3 evolutionarily related DNA-binding proteins. MAX acts as a classic tumor suppressor gene. Normal lymphocytes from patients showed absence of methylation of the MAX promoter and biallelic expression of MAX, which ruled out an imprinting-mediated effect on MAX expression. The ability of these cells to divide, differentiate, and apoptose in the absence of Max demonstrated for the first time that these processes can occur via Max- and possibly Myc-independent mechanisms.

分子量

19-21 kDa

基因ID

4149

UniProt

P61244

途径

Mitotic G1-G1/S Phases