IL18BP 抗体 (AA 29-193)
Quick Overview for IL18BP 抗体 (AA 29-193) (ABIN5692876)
抗原
See all IL18BP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-193
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原理
- Anti-IL18 binding protein/Il18bp Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-IL18 binding protein/Il18bp Antibody Picoband® (ABIN5692876). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. "Entrez Gene: IL18BP interleukin 18 binding protein". 2. Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M (Mar 1999). "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response". Immunity. 10 (1): 127-36. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL18BP (Interleukin 18 Binding Protein (IL18BP))
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别名
- Il18bp
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背景
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Synonyms: Interleukin-18-binding protein, IL-18BP, Interferon gamma-inducing factor-binding protein, Il18bp, Igifbp
Tissue Specificity: Ubiquitous.
Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 43 kDa
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基因ID
- 16068
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UniProt
- Q9Z0M9
抗原
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