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HMBS 抗体 (AA 6-361)

This anti-HMBS antibody is a 兔多克隆 antibody detecting HMBS in WB 和 ELISA. Suitable for 人, 小鼠和大鼠.

Western blot analysis of HMBS using anti-HMBS antibody . (HMBS 抗体 (AA 6-361))

1 image

产品编号 ABIN5692868

发货至: 中国

Quick Overview for HMBS 抗体 (AA 6-361) (ABIN5692868)

抗原

See all HMBS 抗体

HMBS (Hydroxymethylbilane Synthase (HMBS))

适用

66
34
34
3
3
3
2
2
2
2
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

31
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This HMBS antibody is un-conjugated

应用范围

44
13
13
12
8
7
6
4
4
1
1
1

Western Blotting (WB), ELISA

Discover our top product HMBS Primary Antibody

抗原表位
8

6

3

3

2

1

1

1

1

1

1
AA 6-361

原理

Anti-HMBS Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-HMBS Antibody Picoband® (ABIN5692868). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human HMBS recombinant protein (Position: N6-H361).

亚型

IgG
anti-Hydroxymethylbilane Synthase (HMBS) (AA 283-330) antibody
HMBS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (AA 1-361) antibody
HMBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (AA 1-361) antibody
HMBS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E8 unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (AA 85-337) antibody
HMBS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (AA 160-173) antibody
Verified HMBS 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (Internal Region) antibody
HMBS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (AA 1-361) antibody
HMBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) antibody
HMBS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (AA 146-195) antibody
HMBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Hydroxymethylbilane Synthase (HMBS) (N-Term) antibody
HMBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot,0.1-0.5 μg/mL
ELISA,0.1-0.5 μg/mL
1. Lannfelt L, Wetterberg L, Lilius L, Thunell S, Jörnvall H, Pavlu B, Wielburski A, Gellerfors P (November 1989). "Porphobilinogen deaminase in human erythrocytes: purification of two forms with apparent molecular weights of 40 kDa and 42 kDa". Scand. J. Clin. Lab. Invest. 49 (7): 677-84. 2. Louie GV, Brownlie PD, Lambert R, Cooper JB, Blundell TL, Wood SP, Warren MJ, Woodcock SC, Jordan PM (September 1992). "Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site". Nature. 359 (6390): 33-9.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

HMBS (Hydroxymethylbilane Synthase (HMBS))

别名

HMBS

背景

Synonyms: Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase, HMBS, PBGD, UPS
Tissue Specificity: Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells.
Background: Porphobilinogen deaminase (hydroxymethylbilane synthase, or uroporphyrinogen I synthase) is an enzyme that in humans is encoded by the HMBS gene. This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

分子量

45 kDa

基因ID

3145

UniProt

P08397

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