Glycerol Kinase 抗体 (AA 1-180)
Quick Overview for Glycerol Kinase 抗体 (AA 1-180) (ABIN5692865)
抗原
See all Glycerol Kinase (GK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-180
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原理
- Anti-Glycerol kinase/GK Antibody Picoband®
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品牌
- Picoband™
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Rabbit IgG polyclonal antibody for Glycerol kinase detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
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免疫原
- E. coli-derived human Glycerol kinase recombinant protein (Position: M1-S180).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Dipple, K. M., Zhang, Y.-H., Huang, B.-L., McCabe, L. L., Dallongeville, J., Inokuchi, T., Kimura, M., Marx, H. J., Roederer, G. O., Shih, V., Yamaguchi, S., Yoshida, I., McCabe, E. R. B.Glycerol kinase deficiency: evidence for complexity in a single gene disorder. Hum. Genet. 109: 55-62, 2001. 2. Gaudet, D., Arsenault, S., Perusse, L., Vohl, M.-C., St.-Pierre, J., Bergeron, J., Despres, J.-P., Dewar, K., Daly, M. J., Hudson, T., Rioux, J. D. Glycerol as a correlate of impaired glucose tolerance: dissection of a complex system by use of a simple genetic trait. Am. J. Hum. Genet. 66: 1558-1568, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Glycerol Kinase (GK)
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别名
- GK
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背景
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Synonyms: Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase, GK
Tissue Specificity: Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
Background: Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 61 kDa
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基因ID
- 2710
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UniProt
- P32189
抗原
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