Emerin 抗体 (N-Term)
Quick Overview for Emerin 抗体 (N-Term) (ABIN5692852)
抗原
See all Emerin (EMD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-48, N-Term
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原理
- Anti-Emerin EMD Antibody Picoband® (monoclonal, 5A10)
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序列
- MDNYADLSDT ELTTLLRRYN IPHGPVVGST RRLYEKKIFE YETQRRRL
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Emerin EMD Antibody Picoband® (monoclonal, 5A10) (ABIN5692852). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Emerin, different from the related mouse sequence by eight amino acids, and from the related rat sequence by nine amino acids.
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亚型
- IgG1
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anti-Emerin (EMD) (AA 56-167) antibody
EMD 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal EMD-2168 unconjugated
anti-Emerin (EMD) (AA 56-167) antibodyEMD 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal EMD-2167 unconjugated
anti-Emerin (EMD) (AA 1-222) antibodyEMD 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8F5A8 unconjugated
anti-Emerin (EMD) (AA 1-222) antibodyEMD 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Emerin (EMD) (AA 1-110) antibodyEMD 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B9 unconjugated
anti-Emerin (EMD) (AA 1-220) antibodyEMD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Emerin (EMD) antibodyEMD 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Emerin (EMD) (AA 1-254) antibodyEMD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Emerin (EMD) (AA 1-188) antibodyEMD 适用: 人, 兔 WB, IF, ICC 宿主: 小鼠 Monoclonal MANEM1(5D10) unconjugated
anti-Emerin (EMD) (AA 114-183) antibodyEMD 适用: 小鼠, 大鼠, Hamster WB, IF, ICC, EM 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. "Entrez Gene: EMD emerin (Emery-Dreifuss muscular dystrophy)". 2. Lammerding, J, Hsiao, J, Schulze, PC, Kozlov, S, Stewart, CL, Lee, RT (29 August 2005). "Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells.". The Journal of Cell Biology. 170 (5): 781-91. 3. Nagano A, Koga R, Ogawa M, Kurano Y, Kawada J, Okada R, Hayashi YK, Tsukahara T, Arahata K (Mar 1996). "Emerin deficiency at the nuclear membrane in patients with Emery-Dreifuss muscular dystrophy". Nature Genetics. 12 (3): 254-9. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Emerin (EMD)
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别名
- EMD
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背景
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Synonyms: Emerin, EMD, EDMD, STA
Tissue Specificity: Skeletal muscle, heart, colon, testis, ovary and pancreas.
Background: APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G) is a human enzyme encoded by the APOBEC3G gene. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
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分子量
- 34 kDa
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基因ID
- 2010
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UniProt
- P50402
抗原
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