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EGR1 抗体 (AA 239-327)

This anti-EGR1 antibody is a 兔 多克隆 antibody detecting EGR1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5692851
发货至: 中国

Quick Overview for EGR1 抗体 (AA 239-327) (ABIN5692851)

抗原

See all EGR1 抗体
EGR1 (Early Growth Response 1 (EGR1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This EGR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 239-327

    原理

    Anti-Egr1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Egr1 Antibody Picoband® (ABIN5692851). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human Egr1 recombinant protein (Position: A239-R327).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Das, A., Chendil, D., Dey, S., Mohiuddin, M., Mohiuddin, M., Milbrandt, J., Rangnekar, V. M., Ahmed, M. M. Ionizing radiation down-regulates p53 protein in primary Egr-1(-/-) mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J. Biol. Chem. 276: 3279-3286, 2001. 2. Joslin, J. M., Fernald, A. A., Tennant, T. R., Davis, E. M., Kogan, S. C., Anastasi, J., Crispino, J. D., Le Beau, M. M. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood 110: 719-726, 2007.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    EGR1 (Early Growth Response 1 (EGR1))

    别名

    EGR1

    背景

    Synonyms: Early growth response protein 1

    Tissue Specificity: Detected in neutrophils (at protein level).

    Background: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.

    分子量

    75 kDa

    基因ID

    1958

    UniProt

    P18146

    途径

    Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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