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Dynamin 1 抗体 (AA 616-667) (DyLight 488)

This anti-Dynamin 1 antibody is a 兔 多克隆 antibody detecting Dynamin 1 in FACS. Suitable for 人.
产品编号 ABIN7354728
发货至: 中国

Quick Overview for Dynamin 1 抗体 (AA 616-667) (DyLight 488) (ABIN7354728)

抗原

See all Dynamin 1 (DNM1) 抗体
Dynamin 1 (DNM1)

适用

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宿主

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克隆类型

  • 103
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多克隆

标记

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This Dynamin 1 antibody is conjugated to DyLight 488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 616-667

    原理

    Anti-Human Dynamin 1 DyLight® 488 conjugated DNM1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Human Dynamin 1 DyLight® 488 conjugated DNM1 Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

    免疫原

    E. coli-derived human Dynamin 1 recombinant protein (Position: W616-D667).

    亚型

    IgG
  • 应用备注

    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Dhindsa, R. S., Bradrick, S. S., Yao, X., Heinzen, E. L., Petrovski, S., Krueger, B. J., Johnson, M. R., Frankel, W. N., Petrou, S., Boumil, R. M., Goldstein, D. B. Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis. Neurol. Genet. 1: e4, 2015. 2. EuroEPINOMICS-RES Consortium, Epilepsy Phenome/Genome Project, Epi4K Consortium. De novo mutations in synaptic transmission genes including DNM1 cause epileptic encephalopathies. Am. J. Hum. Genet. 95: 360-370, 2014.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
  • 抗原

    Dynamin 1 (DNM1)

    别名

    DNM1

    背景

    Synonyms: Dynamin-1, DNM1, DNM

    Background: Dynamin-1 is a protein that in humans is encoded by the DNM1 gene. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

    分子量

    39 kDa

    基因ID

    1759

    UniProt

    Q05193

    途径

    Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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