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DGCR8 抗体 (AA 561-762)

This anti-DGCR8 antibody is a 兔 多克隆 antibody detecting DGCR8 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5692841
发货至: 中国

Quick Overview for DGCR8 抗体 (AA 561-762) (ABIN5692841)

抗原

See all DGCR8 抗体
DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

适用

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人, 小鼠, 大鼠

宿主

  • 39
  • 6

克隆类型

  • 29
  • 16
多克隆

标记

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This DGCR8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 8
    • 5
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 1
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    AA 561-762

    原理

    Anti-DGCR8 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-DGCR8 Antibody Picoband® (ABIN5692841). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human DGCR8 recombinant protein (Position: K561-Q762).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Han, J., Lee, Y., Yeom, K.-H., Kim, Y.-K., Jin, H., Kim, V. N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18: 3016-3027, 2004. 2. Shiohama, A., Sasaki, T., Noda, S., Minoshima, S., Shimizu, N. Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem. Biophys. Res. Commun. 304: 184-190, 2003.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

    别名

    DGCR8

    背景

    Synonyms: Microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8, DGCR8, C22orf12, DGCRK6, LP4941

    Tissue Specificity: Ubiquitously expressed.

    Background: The DGCR8 microprocessor complex subunit (DiGeorge syndrome chromosomal [or critical] region 8) is a protein that in humans is encoded by the DGCR8 gene. This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

    分子量

    100 kDa

    基因ID

    54487

    途径

    Regulatory RNA Pathways
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