CSTB 抗体 (AA 1-98)
Quick Overview for CSTB 抗体 (AA 1-98) (ABIN5692840)
抗原
See all CSTB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-98
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原理
- Anti-Stefin B CSTB Antibody Picoband® (monoclonal, 2B6)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Stefin B CSTB Antibody Picoband® (monoclonal, 2B6) (ABIN5692840). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Stefin B recombinant protein (Position: M1-F98). Human Stefin B shares 78.6 % amino acid (aa) sequence identity with both mouse and rat Stefin B.
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亚型
- IgG1
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anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal M2-F1 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibodyCSTB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibodyVerified CSTB 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal M1-C1 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibodyCSTB 适用: 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Cystatin B (Stefin B) (CSTB) antibodyCSTB 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 51-98) antibodyCSTB 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibodyCSTB 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C6 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Alakurtti, K., Weber, E., Rinne, R., Theil, G., de Haan, G.-J., Lindhout, D., Salmikangas, P., Saukko, P., Lahtinen, U., Lehesjoki, A.-E. Loss of lysosomal association of cystatin B proteins representing progressive myoclonus epilepsy, EPM1, mutations. Europ. J. Hum. Genet. 13: 208-215, 2005. Note: Erratum: Europ. J. Hum. Genet. 13: 264 only, 2005. 2. Antonarakis, S. Personal Communication. Geneva, Switzerland 4/8/1997. 3. Bespalova, I. N., Adkins, S., Pranzatelli, M., Burmeister, M. Novel cystatin B mutation and diagnostic PCR assay in an Unverricht-Lundborg progressive myoclonus epilepsy patient. Am. J. Med. Genet. 74: 467-471, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CSTB (Cystatin B (Stefin B) (CSTB))
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别名
- CSTB
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背景
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Synonyms: Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Tissue Specificity: Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.
Background: Cystatin B (CSTB), also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.
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分子量
- 14 kDa
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基因ID
- 1476
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UniProt
- P04080
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途径
- Response to Water Deprivation
抗原
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