Cullin 4A 抗体 (AA 494-759)
Quick Overview for Cullin 4A 抗体 (AA 494-759) (ABIN5692838)
抗原
See all Cullin 4A (CUL4A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 494-759
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原理
- Anti-Cullin 4a/CUL4A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cullin 4a/CUL4A Antibody Picoband® (ABIN5692838). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Cullin 4a recombinant protein (Position: M494-A759).
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亚型
- IgG
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anti-Cullin 4A (CUL4A) (AA 1-759) antibody
CUL4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) antibodyCUL4A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) antibodyCUL4A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-100) antibodyCUL4A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-100) antibodyCUL4A 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Cullin 4A (CUL4A) (AA 1-759) antibodyCUL4A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 31-60), (N-Term) antibodyCUL4A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB33954 unconjugated
anti-Cullin 4A (CUL4A) antibodyCUL4A 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (Middle Region) antibodyCUL4A 适用: 人, 小鼠, 大鼠, 马, 兔, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-61) antibodyCUL4A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: CUL4A Cullin 4A". 2. Liu L, Lee S, Zhang J, Peters SB, Hannah J, Zhang Y, Yin Y, Koff A, Ma L, Zhou P (May 2009). "CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis". Molecular Cell. 34 (4): 451-60. 3. Shiyanov P, Nag A, Raychaudhuri P (Dec 1999). "Cullin 4A associates with the UV-damaged DNA-binding protein DDB". The Journal of Biological Chemistry. 274 (50): 35309-12. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cullin 4A (CUL4A)
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别名
- CUL4A
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背景
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Synonyms: Cullin-4A, CUL-4A, CUL4A
Background: Cullin-4A is a protein that in humans is encoded by the CUL4A gene. It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. As a result, CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. Interestingly, a component of a CUL4A complex, Cereblon, was discovered to be a major target of the teratogenic agent thalidomide.
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分子量
- 88 kDa
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基因ID
- 8451
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UniProt
- Q13619
抗原
-
