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- 抗原 See all Bestrophin 1 (BEST1) 抗体
- Bestrophin 1 (BEST1)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Bestrophin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 品牌
- Picoband™
- 序列
- RFIYRLALTE EQQLMFEKLT LYCD
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for Bestrophin detection. Tested with WB, IHC-F, ICC, FCM in Human.
- 免疫原
- A synthetic peptide corresponding to a sequence of human Bestrophin (RFIYRLALTEEQQLMFEKLTLYCD).
- Top Product
- Discover our top product BEST1 Primary Antibody
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anti-Bestrophin 1 (BEST1) antibody
BEST1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 200-300) antibodyBEST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) antibodyBEST1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 1-604) antibodyBEST1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) antibodyBEST1 适用: 人, Pig, 灵长类 WB, IF 宿主: 小鼠 Monoclonal E6-6 unconjugated
anti-Bestrophin 1 (BEST1) (3rd Extracellular Loop), (AA 259-270) antibodyBEST1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) antibodyBEST1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 361-460) antibodyBEST1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Bestrophin 1 (BEST1) (AA 376-585) antibodyBEST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) antibodyBEST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x106 cells - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Bestrophin 1 (BEST1)
- 别名
- BEST1 (BEST1 产品)
- 别名
- CG6264 antibody, Dbest antibody, Dmel\\CG6264 antibody, anon-WO0118547.380 antibody, best antibody, dBest1 antibody, dbest1 antibody, dmBest1 antibody, BEST1 antibody, VMD2 antibody, best-1 antibody, ARB antibody, BEST antibody, BMD antibody, RP50 antibody, TU15B antibody, Bmd antibody, Vmd2 antibody, mBest1 antibody, Bestrophin 1 antibody, bestrophin 1 antibody, Best1 antibody, BEST1 antibody, best1 antibody, Bm1_25500 antibody
- 背景
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Synonyms: Bestrophin-1, TU15B, Vitelliform macular dystrophy protein 2, BEST1, VMD2
Tissue Specificity: Predominantly expressed in the basolateral membrane of the retinal pigment epithelium.
Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
- UniProt
- O76090
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