ACTN3 抗体 (C-Term) (DyLight 488)
Quick Overview for ACTN3 抗体 (C-Term) (DyLight 488) (ABIN7354740)
抗原
See all ACTN3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 574-617, C-Term
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原理
- Anti-Human ACTN3 DyLight® 488 conjugated Antibody
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序列
- EADRERGAIM GIQGEIQKIC QTYGLRPCST NPYITLSPQD INT
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human ACTN3 DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ACTN3, different from the related mouse sequence by five amino acids.
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亚型
- IgG
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Papadimitriou ID, Papadopoulos C, Kouvatsi A, Triantaphyllidis C (April 2008). "The ACTN3 gene in elite Greek track and field athletes". Int J Sports Med 29 (4): 352-5. 2. Yang N, MacArthur DG, Gulbin JP, Hahn AG, Beggs AH, Easteal S, North K (September 2003). "ACTN3 genotype is associated with human elite athletic performance". Am. J. Hum. Genet. 73 (3): 627-31.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- ACTN3 (Actinin, alpha 3 (ACTN3))
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别名
- ACTN3
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背景
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Synonyms: Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3
Tissue Specificity: Expressed only in a subset of type 2 skeletal muscle fibers.
Background: Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants, the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.
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分子量
- 39 kDa
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基因ID
- 89
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UniProt
- Q08043
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途径
- Cell-Cell Junction Organization
抗原
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