Arylsulfatase A 抗体 (C-Term) (DyLight 488)
Quick Overview for Arylsulfatase A 抗体 (C-Term) (DyLight 488) (ABIN5692788)
抗原
See all Arylsulfatase A (ARSA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 454-482, C-Term
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原理
- Anti-Human ARSA DyLight® 488 conjugated Antibody(monoclonal, 4C10)
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序列
- QALKQLQLLK AQLDAAVTFG PSQVARGED
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human ARSA DyLight® 488 conjugated Antibody (monoclonal, 4C10) (ABIN5692787)-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ARSA, different from the related mouse sequence by six amino acids.
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亚型
- IgG2a
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anti-Arylsulfatase A (ARSA) (Internal Region) antibody
Verified ARSA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (Internal Region) antibodyARSA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 1-507) antibodyARSA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 1-507) antibodyARSA 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 210-509) antibodyARSA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 454-482), (C-Term) antibodyARSA 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 21-295) antibodyARSA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Fujii T, Kobayashi T, Honke K et al. (1992). "Proteolytic processing of human lysosomal arylsulfatase A". Biochim. Biophys. Acta 1122 (1): 93-8. 2. Kondo R, Wakamatsu N, Yoshino H et al. (1991)."Identification of a mutation in the arylsulfatase A gene of a patient with adult-type metachromatic leukodystrophy". Am. J. Hum. Genet. 48 (5): 971-8. 3. Matzner U, Herbst E, Hedayati KK, Lüllmann-Rauch R, Wessig C, Schröder S, Eistrup C, Möller C, Fogh J, Gieselmann V (May 2005). "Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy". Hum. Mol. Genet. 14 (9): 1139-52.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- Arylsulfatase A (ARSA)
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别名
- ARSA
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背景
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Synonyms: Arylsulfatase A, ASA, Cerebroside-sulfatase, Arylsulfatase A component B, Arylsulfatase A component C, ARSA
Background: Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
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分子量
- 39 kDa
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基因ID
- 410
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UniProt
- P15289
抗原
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