CD39 抗体
Quick Overview for CD39 抗体 (ABIN5691127)
抗原
See all CD39 (ENTPD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The antibody R22 is directed against human CD39. The antibody has not been tested for cross reactivity with other species.
-
免疫原
- R22 is a rat monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with splenocytes from a WAG/Rij rat immunized with JY cells, a human B lymphoblastoid cell line.
-
亚型
- IgG1
-
-
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-180) antibody
ENTPD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-179) antibodyENTPD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8E9F2 unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-179) antibodyENTPD1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 6H12F9 unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 241-486) antibodyENTPD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 316-474) antibodyENTPD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibodyENTPD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 398-411), (Extracellular) antibodyENTPD1 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibodyENTPD1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibody (FITC)ENTPD1 适用: 人 FACS 宿主: 小鼠 Monoclonal TU66 FITC
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibody (APC)ENTPD1 适用: 人 FACS 宿主: 小鼠 Monoclonal TU66 APC
-
-
应用备注
- The R22 antibody is suitable for the detection of human CD39 antigen by flow cytometry. Human spleen is suitable as a positive control. Optimal antibody dilutions for the different applications should be determined by titration.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Each vial contains 100 μL 1 mg/mL purified monoclonal antibody in phosphate buffered saline (PBS) containing 0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C, or in small aliquots at -20°C.
-
-
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
-
别名
- CD39, Ectonucleoside triphosphate diphosphohydrolase 1
-
背景
- CD39 is a transmembrane cell surface protein, which is a member of the ecto-nucleoside triphosphate diphosphohydrolase (ENTPDase) family. The CD39 Molecule is primarily involved in the metabolism of purine nucleotides, converting extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP) to adenosine monophosphate (AMP). In conjunction with CD73 (5' nucleotidase), CD39 plays a key role in regulating immunity and inflammation through the production of adenosine and purinergic signalling pathways. In addition, CD39 is reported to mediate B cell homotypic adhesion and inhibit ADP-induced platelet aggregation. CD39 was originally identified on Epstein Barr virus transformed B cell lines and described as a B-cell activation marker. However, subsequent studies have shown that CD39 is also expressed on activated T-cells, T-regulatory cells, natural killer cells, tissue macrophages and endothelial cells. Increased expression of CD39 has also been reported in cases of chronic lymphocytic leukaemia and several solid tumours including colorectal and pancreatic cancer suggesting a potential role for CD39 in tumour development and progression.
-
UniProt
- P49961
抗原
-
