IL1RL1 抗体
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北京 101111
Quick Overview for IL1RL1 抗体 (ABIN5690499)
抗原
See all IL1RL1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes soluble human ST2. Detects a band of ~50 kDa by Western blot.
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免疫原
- Recombinant human soluble ST2.
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应用备注
- ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Stable for at least 6 months after receipt when stored at -20°C.
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- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
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别名
- ST2
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背景
- The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
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基因ID
- 9173
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UniProt
- Q01638
抗原
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