WSB1 抗体 (AA 70-120)
Our Local Distributor
北京 101111
Quick Overview for WSB1 抗体 (AA 70-120) (ABIN5690325)
抗原
See all WSB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 70-120
-
特异性
- WSB1 antibody is human specific.
-
纯化方法
- WSB1 antibody is affinity chromatography purified via peptide column.
-
免疫原
-
WSB1 antibody was raised against a 16 amino acid peptide near the amino terminus of human WSB1.
The immunogen is located within amino acids 70 - 120 of WSB1. -
亚型
- IgG
-
-
-
-
应用备注
- WSB1 antibody can be used for detection of WSB1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- WSB1 antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- WSB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))
-
别名
- WSB1
-
背景
- The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).
-
分子量
-
Predicted: 46 kDa
Observed: 46 kDa -
基因ID
- 26118
-
NCBI登录号
- NP_056441
-
UniProt
- Q9Y6I7
抗原
-