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WSB1 抗体 (AA 70-120)

This anti-WSB1 antibody is a 兔 多克隆 antibody detecting WSB1 in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN5690325
发货至: 中国

Quick Overview for WSB1 抗体 (AA 70-120) (ABIN5690325)

抗原

See all WSB1 抗体
WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This WSB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 70-120

    特异性

    WSB1 antibody is human specific.

    纯化方法

    WSB1 antibody is affinity chromatography purified via peptide column.

    免疫原

    WSB1 antibody was raised against a 16 amino acid peptide near the amino terminus of human WSB1.

    The immunogen is located within amino acids 70 - 120 of WSB1.

    亚型

    IgG
  • 应用备注

    WSB1 antibody can be used for detection of WSB1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    WSB1 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    WSB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))

    别名

    WSB1

    背景

    The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).

    分子量

    Predicted: 46 kDa

    Observed: 46 kDa

    基因ID

    26118

    NCBI登录号

    NP_056441

    UniProt

    Q9Y6I7
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