SPIB 抗体 (AA 200-250)
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Quick Overview for SPIB 抗体 (AA 200-250) (ABIN5690267)
抗原
See all SPIB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-250
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特异性
- SPIB antibody is human, mouse and rat reactive. At least four isoforms of SPIB are known to exist, this antibody will detect all but isoform 3.
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纯化方法
- SPIB antibody is affinity chromatography purified via peptide column.
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免疫原
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SPIB antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SPIB.
The immunogen is located within amino acids 200 - 250 of SPIB. -
亚型
- IgG
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应用备注
- SPIB antibody can be used for detection of SPIB by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SPIB antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- SPIB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
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别名
- SPIB
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背景
- SPIB is a member of the ETS transcription factor family that influences lymphoid development and activity and binds the consensus DNA site GGA (A/T) through a unique winged helix-turn-helix motif known as the ETS domain (1). SPIB is found in hematopoietic cells such as B cells and plasmacytoid dendritic cells (DC) (2,3). It promotes the development of plasmacytoid dendritic cells (pDCs) or natural interferon (IFN)-producing cells. SPIB may be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation (3,4).
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分子量
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Predicted: 19, 25, 29 kDa
Observed: 20 kDa -
基因ID
- 6689
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NCBI登录号
- NP_003112
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UniProt
- Q01892
抗原
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