RHOT1 抗体 (AA 40-90)
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北京 101111
Quick Overview for RHOT1 抗体 (AA 40-90) (ABIN5690226)
抗原
See all RHOT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90
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特异性
- RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist, this antibody will detect all three isoforms.
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纯化方法
- RHOT1 antibody is affinity chromatography purified via peptide column.
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免疫原
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RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1.
The immunogen is located within amino acids 40 - 90 of RHOT1. -
亚型
- IgG
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应用备注
- RHOT1 antibody can be used for detection of RHOT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RHOT1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- RHOT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))
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别名
- RHOT1
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背景
- The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4).
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分子量
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Predicted: 76 kDa
Observed: 78 kDa -
基因ID
- 55288
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NCBI登录号
- NP_001028740
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UniProt
- Q8IXI2
抗原
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