PIK3R4 抗体 (AA 1290-1340)
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北京 101111
Quick Overview for PIK3R4 抗体 (AA 1290-1340) (ABIN5690100)
抗原
See all PIK3R4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1290-1340
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特异性
- PIK3R4 antibody is human, mouse and rat reactive.
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纯化方法
- PIK3R4 antibody is affinity chromatography purified via peptide column.
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免疫原
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PIK3R4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PIK3R4.
The immunogen is located within amino acids 1290 - 1340 of PIK3R4. -
亚型
- IgG
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应用备注
- PIK3R4 antibody can be used for detection of PIK3R4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PIK3R4 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- PIK3R4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- PIK3R4 (Phosphoinositide 3-kinase Regulatory Subunit 4 (PIK3R4))
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别名
- PIK3R4
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背景
- PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4, also known as VPS15) is a 150kD adaptor protein that enhances the lipid kinase activity of PIK3 complexes and may be involved in regulating membrane trafficking late in the endocytic pathway and autophagy (1,2). PIK3R4 is ubiquitously expressed and contains 7 WD repeats, 3 HEAT repeats and 1 protein kinase domain (1). PIK3R4 is crucial for VPS34 function and is necessary for autophagosome formation in multicellular animals and reveal an important role of VPS15 in cellular protection against ubiquitin-positive protein aggregates (3-5).
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分子量
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Predicted: 149 kDa
Observed: 140 kDa -
基因ID
- 30849
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NCBI登录号
- NP_055417
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UniProt
- Q99570
抗原
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