PHC3 antibody can be used for detection of PHC3 by Western blot at 1 - 2 μ,g/mL.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
PHC3 antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
PHC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
PHC3
(Polyhomeotic Homolog 3 (PHC3))
别名
PHC3
背景
Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4).