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PHC3 抗体 (AA 240-290)

This anti-PHC3 antibody is a 兔 多克隆 antibody detecting PHC3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5690097
发货至: 中国

Quick Overview for PHC3 抗体 (AA 240-290) (ABIN5690097)

抗原

See all PHC3 抗体
PHC3 (Polyhomeotic Homolog 3 (PHC3))

适用

  • 22
  • 13
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 21
  • 1

克隆类型

  • 22
多克隆

标记

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PHC3 antibody is un-conjugated

应用范围

  • 11
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 240-290

    特异性

    PHC3 antibody is human, mouse and rat specific. At least six isoforms of PHC3 are known to exist.

    纯化方法

    PHC3 antibody is affinity chromatography purified via peptide column.

    免疫原

    PHC3 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHC3.

    The immunogen is located within amino acids 240 - 290 of PHC3.

    亚型

    IgG
  • 应用备注

    PHC3 antibody can be used for detection of PHC3 by Western blot at 1 - 2 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PHC3 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PHC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    PHC3 (Polyhomeotic Homolog 3 (PHC3))

    别名

    PHC3

    背景

    Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4).

    分子量

    Predicted: 109 kDa

    Observed: 120 kDa

    基因ID

    80012

    NCBI登录号

    NP_079223

    UniProt

    Q8NDX5
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