KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.
纯化方法
KIRREL3 antibody is affinity chromatography purified via peptide column.
免疫原
KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.
The immunogen is located within amino acids 20 - 70 of KIRREL3.
KIRREL3
适用: 小鼠
FACS, IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 555
应用备注
KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
KIRREL3 antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
KIRREL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
KIRRE antibody, MRD4 antibody, NEPH2 antibody, PRO4502 antibody, 1500010O20Rik antibody, 2900036G11Rik antibody, SST4 antibody, mKIAA1867 antibody, kirre like nephrin family adhesion molecule 3 antibody, kin of IRRE like 3 (Drosophila) antibody, KIRREL3 antibody, Kirrel3 antibody
背景
KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).