IQSEC2 抗体 (AA 1380-1430)
Quick Overview for IQSEC2 抗体 (AA 1380-1430) (ABIN5690019)
抗原
See all IQSEC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1380-1430
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特异性
- IQSEC2 antibody is human, mouse and rat reactive. At least two isoforms of IQSEC2 are known to exist, this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1.
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纯化方法
- IQSEC2 antibody is affinity chromatography purified via peptide column.
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免疫原
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IQSEC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IQSEC2.
The immunogen is located within amino acids 1380 - 1430 of IQSEC2. -
亚型
- IgG
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anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 451-484) antibody
IQSEC2 适用: 人 WB 宿主: 兔 Polyclonal RB52674 unconjugated
anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 1-949) antibodyIQSEC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 351-400) antibodyIQSEC2 适用: 小鼠, 人, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IQSEC2 antibody can be used for detection of IQSEC2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IQSEC2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- IQSEC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
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别名
- IQSEC2
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背景
- ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. Similar to the related protein IQSEC1, IQSEC2 is a guanine nucleotide exchange protein for ARF1 and ARF6 that belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1,2). IQSEC2 is a major component of the postsynaptic density (PSD) and colocalizes with PSD-95. It has been suggested to modulate the functions of the ARF proteins (1). Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation (3).
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分子量
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Predicted: 104, 133, 141, 164 kDa
Observed: 140 kDa -
基因ID
- 23096
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NCBI登录号
- NP_001104595
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UniProt
- Q5JU85
抗原
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