IQSEC1 抗体 (AA 60-110)
This anti-IQSEC1 antibody is a 兔 多克隆 antibody detecting IQSEC1 in WB, ELISA, ICC 和 IF. Suitable for 小鼠, 人 和 大鼠.
Quick Overview for IQSEC1 抗体 (AA 60-110) (ABIN5690018)
抗原
See all IQSEC1 抗体
IQSEC1
(IQ Motif and Sec7 Domain 1 (IQSEC1))
适用
小鼠, 人, 大鼠
宿主
兔
克隆类型
多克隆
标记
This IQSEC1 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
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抗原表位
- AA 60-110
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特异性
- IQSEC1 antibody is human, mouse and rat reactive. At least four isoforms of IQSEC1 are known to exist. IQSEC1 antibody is predicted to not cross-react with IQSEC2.
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纯化方法
- IQSEC1 antibody is affinity chromatography purified via peptide column.
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免疫原
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IQSEC1 antibody was raised against a 19 amino acid peptide near the amino terminus of human IQSEC1.
The immunogen is located within amino acids 60 - 110 of IQSEC1. -
亚型
- IgG
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anti-IQ Motif and Sec7 Domain 1 (IQSEC1) (N-Term) antibody
IQSEC1 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif and Sec7 Domain 1 (IQSEC1) (AA 180-380) antibodyIQSEC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IQSEC1 antibody can be used for detection of IQSEC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 2 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IQSEC1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- IQSEC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IQSEC1 (IQ Motif and Sec7 Domain 1 (IQSEC1))
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别名
- IQSEC1
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背景
- ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. IQSEC1 (GEP100/BRAG2), a guanine nucleotide exchange protein for ARF6, belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1). As a known activator of ARF6, IQSEC1 regulates cell surface levels of Beta1 integrin and its knockdown blocked tumour metastasis (2,3). IQSEC1 links EGFR signaling to ARF6 activation and may contribute to the cancer metastasis and malignancy (4).
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分子量
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Predicted: 106 kDa
Observed: 103 kDa -
基因ID
- 9922
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NCBI登录号
- NP_055684
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UniProt
- Q6DN90
抗原
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