GOLGA5 抗体 (AA 540-590)
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北京 101111
Quick Overview for GOLGA5 抗体 (AA 540-590) (ABIN5689977)
抗原
See all GOLGA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 540-590
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特异性
- GOLGA5 antibody is human, mouse and rat reactive. Two isoforms of GOLGA5 exist due to alternative splicing events.
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纯化方法
- GOLGA5 Antibody is affinity chromatography purified via peptide column.
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免疫原
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GOLGA5 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GOLGA5.
The immunogen is located within amino acids 540 - 590 of GOLGA5. -
亚型
- IgG
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应用备注
- GOLGA5 antibody can be used for detection of GOLGA5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GOLGA5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- GOLGA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GOLGA5 (Golgin A5 (GOLGA5))
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别名
- GOLGA5
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背景
- GOLGA5 Antibody: GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1). It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2). As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4). Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5).
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分子量
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Predicted: 64, 80 kDa
Observed: 65, 78 kDa -
基因ID
- 9950
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NCBI登录号
- NP_005104
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UniProt
- Q8TBA6
抗原
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