ERAP1 抗体 (AA 730-780)
Our Local Distributor
北京 101111
Quick Overview for ERAP1 抗体 (AA 730-780) (ABIN5689955)
抗原
See all ERAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 730-780
-
特异性
- ERAP1 antibody is human and mouse reactive. At least two isoforms of ERAP1 are known to exist, this antibody will detect both isoforms. ERAP1 antibody is predicted to not cross-react with ERAP2.
-
纯化方法
- ERAP1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
-
ERAP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERAP.
The immunogen is located within amino acids 730 - 780 of ERAP1 . -
亚型
- IgG
-
-
-
-
应用备注
- ERAP1 antibody can be used for detection of ERAP1 by Western blot at 1 - 2 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- ERAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- ERAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
-
别名
- ERAP1
-
背景
- The endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1), a member of the peptidase M1 family, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). It is also designated as adipocyte-derived leucine aminopeptidase (A-LAP), puromycin-insensitive leucine-specific aminopeptidase (PILS-AP) and aminopeptidase regulator of TNFR1 shedding (ARTS-1) (3). ERAP1 is localized to the lumen of the ER and induced by interferon. It may be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (3,4).
-
分子量
-
Predicted: 104 kDa
Observed: 105kDa -
基因ID
- 51752
-
NCBI登录号
- NP_057526
-
UniProt
- Q9NZ08
抗原
-