DNAJC13 抗体 (AA 1940-1990)
This anti-DNAJC13 antibody is a 兔 多克隆 antibody detecting DNAJC13 in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
Quick Overview for DNAJC13 抗体 (AA 1940-1990) (ABIN5689948)
抗原
DNAJC13
(DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This DNAJC13 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 1940-1990
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特异性
- DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist, this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.
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纯化方法
- DNAJC13 antibody is affinity chromatography purified via peptide column.
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免疫原
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DNAJC13 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DNAJC13.
The immunogen is located within amino acids 1940 - 1990 of DNAJC13. -
亚型
- IgG
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应用备注
- DNAJC13 antibody can be used for detection of DNAJC13 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DNAJC13 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- DNAJC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))
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别名
- DNAJC13
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背景
- DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans (1). It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles (2). DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor (3).
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分子量
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Predicted: 249 kDa
Observed: 249 kDa -
基因ID
- 23317
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NCBI登录号
- NP_056083
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UniProt
- O75165
抗原
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